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1

Therapeutic implications of germline genetic findings in cancer

Thavaneswaran, Subotheni, Rath, Emma, Tucker, Kathy, Joshua, Anthony M., Hess, Dominique, Pinese, Mark, Ballinger, Mandy L., Thomas, David M.

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2019

Language:

english

File:

PDF, 963 KB

english, 2019

2

Smad2-dependent glycosaminoglycan elongation in aortic valve interstitial cells enhances binding of LDL to proteoglycans

Osman, Narin, Grande-Allen, K. Jane, Ballinger, Mandy L., Getachew, Robel, Marasco, Silvana, O'Brien, Kevin D., Little, Peter J.

Journal:

Cardiovascular Pathology

Year:

2013

Language:

english

File:

PDF, 1.41 MB

english, 2013

3

Timing and context: important considerations in the return of genetic results to research participants

McBride, Kate A., Hallowell, Nina, Tattersall, Martin H. N., Kirk, Judy, Ballinger, Mandy L., Thomas, David M., Mitchell, Gillian, Young, Mary-Anne

Journal:

Journal of Community Genetics

Year:

2016

File:

PDF, 276 KB

2016

4

Monogenic and polygenic determinants of sarcoma risk: an international genetic study

Ballinger, Mandy L, Goode, David L, Ray-Coquard, Isabelle, James, Paul A, Mitchell, Gillian, Niedermayr, Eveline, Puri, Ajay, Schiffman, Joshua D, Dite, Gillian S, Cipponi, Arcadi, Maki, Robert G, Bro

Journal:

The Lancet Oncology

Year:

2016

Language:

english

File:

PDF, 415 KB

english, 2016

5

Anti-proliferative activity of oral anti-hyperglycemic agents on human vascular smooth muscle cells: thiazolidinediones (glitazones) have enhanced activity under high glucose conditions

Peter J Little, Narin Osman, Stephanie T de Dios, Nelly Cemerlang, Mandy Ballinger, Julie Nigro

Journal:

Cardiovascular Diabetology

Year:

2007

Language:

english

File:

PDF, 270 KB

english, 2007

6

TGF-β stimulates biglycan synthesis via p38 and ERK phosphorylation of the linker region of Smad2

Micah L. Burch, Sundy N. Y. Yang, Mandy L. Ballinger, Robel Getachew, Narin Osman, Peter J. Little

Journal:

Cellular and Molecular Life Sciences

Year:

2010

Language:

english

File:

PDF, 734 KB

english, 2010

7

Glycated and carboxy-methylated proteins do not directly activate human vascular smooth muscle cells

Ballinger, Mandy L., Thomas, Merlin C., Nigro, Julie, Ivey, Melanie E., Dilley, Rodney J., Little, Peter J.

Journal:

Kidney International

Year:

2005

Language:

english

File:

PDF, 280 KB

english, 2005

8

Characterisation of Ki11502 as a potent inhibitor of PDGF β receptor-mediated proteoglycan synthesis in vascular smooth muscle cells

Robel Getachew, Mandy L. Ballinger, Micah L. Burch, Peter J. Little, Narin Osman

Journal:

European Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 706 KB

english, 2010

9

Regulation of the atherogenic properties of vascular smooth muscle proteoglycans by oral anti-hyperglycemic agents

Stephanie T. de Dios, Karen V. Frontanilla, Julie Nigro, Mandy L. Ballinger, Melanie E. Ivey, Elizabeth A. Cawson, Peter J. Little

Journal:

Journal of Diabetes and its Complications

Year:

2007

Language:

english

File:

PDF, 1003 KB

english, 2007

10

Imatinib inhibits vascular smooth muscle proteoglycan synthesis and reduces LDL binding in vitro and aortic lipid deposition in vivo

Mandy L. Ballinger, Narin Osman, Kazuhiko Hashimura, Judy B. de Haan, Karin Jandeleit-Dahm, Terri Allen, Lisa R. Tannock, John C. Rutledge, Peter J. Little

Journal:

Journal of Cellular and Molecular Medicine

Year:

2010

Language:

english

File:

PDF, 905 KB

english, 2010

11

Inherited andde novogermline TP53 mutations in adult-onset sarcoma

David M Thomas, Mandy L Ballinger, International Sarcoma Kindred Study Consortium

Journal:

Hereditary Cancer in Clinical Practice

Year:

2012

Language:

english

File:

PDF, 73 KB

english, 2012

12

An increased incidence of Hodgkin's lymphoma in patients with adult-onset sarcoma

Megan E Downing, Gillian S Dite, Mandy L Ballinger, The International Sarcoma Kindred Study Consortium

Journal:

Clinical Sarcoma Research

Year:

2012

Language:

english

File:

PDF, 160 KB

english, 2012

13

Genistein inhibits PDGF-stimulated proteoglycan synthesis in vascular smooth muscle without blocking PDGFβ receptor phosphorylation

Peter J. Little, Robel Getachew, Hossein Babaahmadi Rezaei, Estella Sanchez-Guerrero, Levon M. Khachigian, Haitao Wang, Sufen Liao, Wenhua Zheng, Mandy L. Ballinger, Narin Osman

Journal:

Archives of Biochemistry and Biophysics

Year:

2012

Language:

english

File:

PDF, 624 KB

english, 2012

14

Endothelin-1 activates ETA receptors on human vascular smooth muscle cells to yield proteoglycans with increased binding to LDL

Mandy L. Ballinger, Melanie E. Ivey, Narin Osman, Walter G. Thomas, Peter J. Little

Journal:

Atherosclerosis

Year:

2009

Language:

english

File:

PDF, 932 KB

english, 2009

15

The attitudes of people with sarcoma and their family towards genomics and incidental information arising from genetic research

Young, Mary-Anne, Herlihy, Amy, Mitchell, Gillian, Thomas, David M, Ballinger, Mandy, Tucker, Kathy, Lewis, Craig R, Neuhaus, Susan, Halliday, Jane

Journal:

Clinical Sarcoma Research

Year:

2013

Language:

english

File:

PDF, 207 KB

english, 2013

16

Li-Fraumeni syndrome: cancer risk assessment and clinical management

McBride, Kate A., Ballinger, Mandy L., Killick, Emma, Kirk, Judy, Tattersall, Martin H. N., Eeles, Rosalind A., Thomas, David M., Mitchell, Gillian

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2014

Language:

english

File:

PDF, 714 KB

english, 2014

17

Growth factor-mediated hyper-elongation of glycosaminoglycan chains on biglycan requires transcription and translation

Yang, Sundy N. Y., Burch, Micah L., Getachew, Robel, Ballinger, Mandy L., Osman, Narin, Little, Peter J.

Journal:

Archives of Physiology and Biochemistry

Year:

2009

Language:

english

File:

PDF, 905 KB

english, 2009

18

Suramin inhibits PDGF-stimulated receptor phosphorylation, proteoglycan synthesis and glycosaminoglycan hyperelongation in human vascular smooth muscle cells

Little, Peter J., Rostam, Muhamad Ashraf, Piva, Terrence J., Getachew, Robel, Kamato, Danielle, Guidone, Daniel, Ballinger, Mandy L., Zheng, Wenhua, Osman, Narin

Journal:

Journal of Pharmacy and Pharmacology

Year:

2013

Language:

english

File:

PDF, 979 KB

english, 2013

19

Clinical implications of genomics for cancer risk genetics

Thomas, David M, James, Paul A, Ballinger, Mandy L

Journal:

The Lancet Oncology

Year:

2015

Language:

english

File:

PDF, 182 KB

english, 2015

20

Anti-Atherogenic Role of Peroxisome Proliferator-Activated Receptor Ligands

Nigro, Julie, Ballinger, Mandy, Osman, Narin, Dart, Anthony, Little, Peter

Journal:

Current Cardiology Reviews

Year:

2005

Language:

english

File:

PDF, 159 KB

english, 2005

21

p38 MAP Kinase Mediated Proteoglycan Synthesis as a Target for the Prevention of Atherosclerosis

Osman, Narin, Ballinger, Mandy, Dadlani, Harsha, Getachew, Robel, Burch, Micah, Little, Peter

Journal:

Cardiovascular & Haematological Disorders - Drug Targets(Formerly Current Drug Targets - Cardiovascular & Hematological Disorders)

Year:

2008

Language:

english

File:

PDF, 205 KB

english, 2008

22

Timing and context: important considerations in the return of genetic results to research participants

McBride, Kate A., Hallowell, Nina, Tattersall, Martin H. N., Kirk, Judy, Ballinger, Mandy L., Thomas, David M., Mitchell, Gillian, Young, Mary-Anne

Journal:

Journal of Community Genetics

Year:

2016

Language:

english

File:

PDF, 276 KB

english, 2016

23

PDGF β-Receptor Kinase Activity and ERK1/2 Mediate Glycosaminoglycan Elongation on Biglycan and Increases Binding to LDL

Getachew, Robel, Ballinger, Mandy L., Burch, Micah L., Reid, Julianne J., Khachigian, Levon M., Wight, Thomas N., Little, Peter J., Osman, Narin

Journal:

Year:

2010

Language:

english

File:

PDF, 598 KB

english, 2010

24

Phosphorylated Troglitazone Activates PPARγ and Inhibits Vascular Smooth Muscle Cell Proliferation and Proteoglycan Synthesis

Little, Peter J, Ballinger, Mandy L, Survase, Soniya, Osman, Narin, Ogru, Esra, Geytenbeek, Stephen, Bruemmer, Dennis, Nigro, Julie

Journal:

Journal of Cardiovascular Pharmacology

Year:

2008

Language:

english

File:

PDF, 415 KB

english, 2008

25

Calcific Aortic Valve Disease and Hypertension

Dadlani, Harsha, Osman, Narin, Ballinger, Mandy, Marasco, Silvana, Little, Peter

Journal:

Current Hypertension Reviews

Year:

2008

Language:

english

File:

PDF, 308 KB

english, 2008

26

International survey of awareness of genetic risk in the clinical sarcoma community

McBride, Kate A, Schlub, Timothy E, Ballinger, Mandy L, Thomas, David M, Tattersall, Martin HN

Journal:

Asia-Pacific Journal of Clinical Oncology

Year:

2016

Language:

english

File:

PDF, 138 KB

english, 2016

27

Etiologic, environmental and inherited risk factors in sarcomas

Thomas, David M., Ballinger, Mandy L.

Journal:

Journal of Surgical Oncology

Year:

2015

Language:

english

File:

PDF, 96 KB

english, 2015

28

Pyrido-Pyrimidine Derivative CYC10424 Inhibits Glycosaminoglycan Changes on Vascular Smooth Muscle-derived Proteoglycans and Reduces Lipoprotein Binding

Ballinger, Mandy L, Osman, Narin, Wilks, Andrew F, Su, Stephen, Burns, Christopher J, Bu, Xianyong, Little, Peter J

Journal:

Journal of Cardiovascular Pharmacology

Year:

2008

Language:

english

File:

PDF, 436 KB

english, 2008

29

Surveillance recommendations for patients with germline TP53 mutations

Ballinger, Mandy L., Mitchell, Gillian, Thomas, David M.

Journal:

Current Opinion in Oncology

Year:

2015

Language:

english

File:

PDF, 218 KB

english, 2015

30

Sociodemographic, psychosocial and clinical factors associated with uptake of genetic counseling for hereditary cancer: a systematic review

Willis, Amanda M., Smith, Sian K., Meiser, Bettina, Ballinger, Mandy L., Thomas, David M., Young, Mary-Anne

Journal:

Clinical Genetics

Year:

2016

Language:

english

File:

PDF, 1.08 MB

english, 2016

31

Sarcoma and germ-line DICER1 mutations – Authors’ reply

Ballinger, Mandy L, Thomas, David M

Journal:

The Lancet Oncology

Year:

2016

Language:

english

File:

PDF, 32 KB

english, 2016

32

Psychosocial morbidity inTP53mutation carriers: is whole-body cancer screening beneficial?

McBride, Kate A., Ballinger, Mandy L., Schlub, Timothy E., Young, Mary-Anne, Tattersall, Martin H. N., Kirk, Judy, Eeles, Ros, Killick, Emma, Walker, Leslie G., Shanley, Sue, Thomas, David M., Mitchel

Journal:

Familial Cancer

Year:

2017

Language:

english

File:

PDF, 716 KB

english, 2017

33

Estimating TP53 Mutation Carrier Probability in Families with Li-Fraumeni Syndrome Using LFSPRO

Peng, Gang, Bojadzieva, Jasmina, Ballinger, Mandy L., Li, Jialu, Blackford, Amanda L., Mai, Phuong L., Savage, Sharon A., Thomas, David M, Strong, Louise C, Wang, Wenyi

Journal:

Cancer Epidemiology Biomarkers & Prevention

Year:

2017

Language:

english

File:

PDF, 373 KB

english, 2017

34

Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice

Leroy, Bernard, Ballinger, Mandy L., Baran-Marszak, Fanny, Bond, Gareth L., Braithwaite, Antony, Concin, Nicole, Donehower, Lawrence A., El-Deiry, Wafik S., Fenaux, Pierre, Gaidano, Gianluca, Langerød

Journal:

Cancer Research

Year:

2017

Language:

english

File:

PDF, 419 KB

english, 2017

35

Baseline Surveillance in Li-Fraumeni Syndrome Using Whole-Body Magnetic Resonance Imaging

Ballinger, Mandy L., Best, Ana, Mai, Phuong L., Khincha, Payal P., Loud, Jennifer T., Peters, June A., Achatz, Maria Isabel, Chojniak, Rubens, Balieiro da Costa, Alexandre, Santiago, Karina Miranda, G

Journal:

Year:

2017

Language:

english

File:

PDF, 329 KB

english, 2017

36

Surveillance in Germline TP53 Mutation Carriers Utilizing Whole-Body Magnetic Resonance Imaging

Ballinger, Mandy L., Ferris, Nicholas J., Moodie, Kate, Mitchell, Gillian, Shanley, Sue, James, Paul A., Thomas, David M.

Journal:

Year:

2017

Language:

english

File:

PDF, 120 KB

english, 2017

37

Development and Pilot Testing of a Decision Aid for Genomic Research Participants Notified of Clinically Actionable Research Findings for Cancer Risk

Willis, Amanda M., Smith, Sian K., Meiser, Bettina, Ballinger, Mandy L., Thomas, David M., Tattersall, Martin, Young, Mary-Anne

Journal:

Journal of Genetic Counseling

Year:

2018

Language:

english

File:

PDF, 1.12 MB

english, 2018

38

A comparison of Australian and French families affected by sarcoma: perceptions of genetics and incidental findings

Rasmussen, Victoria, Forrest, Laura E, Rogasik, Muriel, Girodet, Magali, Meeus, Pierre, Sunyach, Marie-Pierre, Blay, Jean-Yves, Bally, Olivia, Brahmi, Mehdi, Ballinger, Mandy L, Niedermayr, Eveline, T

Journal:

Personalized Medicine

Year:

2018

Language:

english

File:

PDF, 332 KB

english, 2018

39

The PiGeOn project: protocol for a longitudinal study examining psychosocial, behavioural and ethical issues and outcomes in cancer tumour genomic profiling

Best, Megan, Newson, Ainsley J., Meiser, Bettina, Juraskova, Ilona, Goldstein, David, Tucker, Kathy, Ballinger, Mandy L., Hess, Dominique, Schlub, Timothy E., Biesecker, Barbara, Vines, Richard, Vines

Journal:

Year:

2018

Language:

english

File:

PDF, 673 KB

english, 2018

40

The PiGeOn project: protocol of a longitudinal study examining psychosocial and ethical issues and outcomes in germline genomic sequencing for cancer

Best, Megan, Newson, Ainsley J., Meiser, Bettina, Juraskova, Ilona, Goldstein, David, Tucker, Kathy, Ballinger, Mandy L., Hess, Dominique, Schlub, Timothy E., Biesecker, Barbara, Vines, Richard, Vines

Journal:

Year:

2018

Language:

english

File:

PDF, 558 KB

english, 2018

41

Cancer Molecular Screening and Therapeutics (MoST): a framework for multiple, parallel signal-seeking studies of targeted therapies for rare and neglected cancers

Thavaneswaran, Subotheni, Sebastian, Lucille, Ballinger, Mandy, Best, Megan, Hess, Dominique, Lee, Chee K, Sjoquist, Katrin M, Hague, Wendy E, Butow, Phyllis N, Simes, R John, Thomas, David

Journal:

The Medical Journal of Australia

Year:

2018

Language:

english

File:

PDF, 308 KB

english, 2018

42

Translating genomic risk into an early detection strategy for sarcoma

Ballinger, Mandy L, Pinese, Mark, Thomas, David M

Journal:

Genes, Chromosomes and Cancer

Year:

2018

Language:

english

File:

PDF, 1.37 MB

english, 2018

43

New Approaches to Regulating the Chondroitin/Dermatan Sulfate Glycosaminoglycan Component of the Vascular Extracellular Matrix

Nigro, Julie, Ballinger, Mandy L., Survase, Soniya, Osman, Narin, J. Little, Peter

Journal:

The Scientific World JOURNAL

Year:

2005

File:

PDF, 1.12 MB

2005

44

A quantitative model to predict pathogenicity of missense variants in the TP53 gene

Fortuno, Cristina, Cipponi, Arcadi, Ballinger, Mandy L., Tavtigian, Sean V., Olivier, Magali, Ruparel, Vatsal, Haupt, Ygal, Haupt, Sue, International Sarcoma Kindred Study,, Tucker, Kathy, Spurdle, A

Journal:

Year:

2019

File:

PDF, 512 KB

2019

45

Who should access Germline Genome Sequencing? A mixed methods study of patient views

Best, Megan C., Butow, Phyllis, Jacobs, Chris, Savard, Jacqueline, Biesecker, Barbara, Ballinger, Mandy L., Bartley, Nicci, Davies, Grace, Napier, Christine E., Smit, Amelia K., Thomas, David M., News

Journal:

Clinical Genetics

Year:

2019

Language:

english

File:

PDF, 1.62 MB

english, 2019

46

Penetrance of different cancer types in families with Li-Fraumeni syndrome: a validation study using multi-center cohorts

Shin, Seung Jun, Dodd-Eaton, Elissa B, Peng, Gang, Bojadzieva, Jasmina, Chen, Jingxiao, Amos, Christopher I., Frone, Megan N, Khincha, Payal, Mai, Phuong L., Savage, Sharon A., Ballinger, Mandy L., Th

Journal:

Cancer Research

Year:

2019

Language:

english

File:

PDF, 2.12 MB

english, 2019

47

Penetrance of different cancer types in families with Li-Fraumeni syndrome: a validation study using multi-center cohorts

Shin, Seung Jun, Dodd-Eaton, Elissa B, Peng, Gang, Bojadzieva, Jasmina, Chen, Jingxiao, Amos, Christopher I., Frone, Megan N, Khincha, Payal, Mai, Phuong L., Savage, Sharon A., Ballinger, Mandy L., Th

Journal:

Cancer Research

Year:

2019

File:

PDF, 2.12 MB

2019

48

Heritable cancer risk in the genomic era

Ballinger, Mandy L., Thomas, David

Journal:

Year:

2020

Language:

english

File:

PDF, 63 KB

english, 2020

49

Author Correction: Diagnosis of fusion genes using targeted RNA sequencing

Heyer, Erin E., Deveson, Ira W., Wooi, Danson, Selinger, Christina I., Lyons, Ruth J., Hayes, Vanessa M., OâToole, Sandra A., Ballinger, Mandy L., Gill, Devinder, Thomas, David M., Mercer, Tim R., B

Journal:

Nature Communications

Year:

2020

File:

PDF, 355 KB

2020

50

Advanced Cancer Patient Knowledge of and Attitudes towards Tumor Molecular Profiling

Davies, Grace, Butow, Phyllis, Napier, Christine E., Bartley, Nicci, Juraskova, Ilona, Meiser, Bettina, Ballinger, Mandy L., Thomas, David M., Schlub, Timothy E., Best, Megan C.

Journal:

Translational Oncology

Year:

2020

File:

PDF, 388 KB

2020